A new type of transfusion-dependent congenital dyserythropoietic anemia
نویسندگان
چکیده
منابع مشابه
A new type of transfusion-dependent congenital dyserythropoietic anemia.
Cases of congenital dyserythropoietic anemia (CDA) that do not conform to any of the three classical types often present diagnostic difficulties and are at risk of developing secondary hemochromatosis. Here, we report a case of a six year old boy with transfusion dependency and gross abnormalities of the erythroblasts.
متن کاملCongenital dyserythropoietic anemia type III.
BACKGROUND AND OBJECTIVES Congenital dyserythropoietic anemia type III (CDA-III) is a group of very rare disorders characterized by similar bone marrow morphology. The clinical picture is characterized by hemolytic anemia and dramatic bone marrow changes dominated by active erythropoiesis with big multinucleated erythroblasts. The aim of this review is to describe the clinical manifestations, l...
متن کاملA case of congenital dyserythropoietic anemia type IV
Congenital dyserythropoietic anemias (CDAs) are displayed by ineffective erythropoiesis. The wide variety of phenotypes observed in CDA patients makes differential diagnosis difficult; identification of the genetic variants is crucial in clinical management. We report the fifth case of a patient with unclassified CDAs, after genetic study, with CDA type IV.
متن کاملGenetic Heterogeneity of Congenital Dyserythropoietic Anemia Type II
Congenital dyserythropoietic anemia type II (CDA-II, CDAN2, or HEMPAS) (MIM224100) is an autosomal recessive trait and it represents the most frequent form of congenital dyserythropoiesis.1 It is characterized by normocytic anemia, variable jaundice, and hepatosplenomegaly. Gallbladder disease and secondary hemochromatosis are frequent complications. Bone marrow histology shows binucleated and ...
متن کاملGenetic Heterogeneity of Congenital Dyserythropoietic Anemia Type II
Congenital dyserythropoietic anemia type II (CDA-II, CDAN2, or HEMPAS) (MIM224100) is an autosomal recessive trait and it represents the most frequent form of congenital dyserythropoiesis.1 It is characterized by normocytic anemia, variable jaundice, and hepatosplenomegaly. Gallbladder disease and secondary hemochromatosis are frequent complications. Bone marrow histology shows binucleated and ...
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ژورنال
عنوان ژورنال: Haematologica
سال: 2007
ISSN: 0390-6078,1592-8721
DOI: 10.3324/haematol.11594